منابع مشابه
Eliminating the improbable: Sherlock Holmes and standards of evidence in the genomic age.
In 2003, Shearman and colleagues reported that a common variant in the estrogen receptor-alpha gene (ESR1 IVS1 397 C allele) occurred more frequently in male subjects with myocardial infarction (MI) than in those free of MI.1 The following year, Schuit et al described an association between the common haplotype containing the alternate (T) allele and MI, but only in women.2 In this issue of Cir...
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Some risks have extremely high stakes. For example, a worldwide pandemic or asteroid impact could potentially kill more than a billion people. Comfortingly, scientific calculations often put very low probabilities on the occurrence of such catastrophes. In this paper, we argue that there are important new methodological problems which arise when assessing global catastrophic risks and we focus ...
متن کاملImprobable Creativity
We begin with a number of basic facts about creativity and a brief history of the idea. These provide criteria that any definition of the term should meet and help guide us to a new definition of creativity. This definition is independent of cultural appropriateness or the perceived value of creative objects, ideas which have encumbered previous investigations. We briefly defend our definition ...
متن کاملThe Probability of the Improbable: Societynature Coevolution
This article aims to show how evolutionary theory, social-metabolism and sociological systems theory can be utilized to develop a concept of society–nature coevolution. The article begins with a conception of industrialization as a sociometabolic transition, that is, a major transformation in the energetic and consequently material basis of society. This transition to industrial metabolism was ...
متن کاملKorotkoff Sounds - The Improbable also Occurs
Very few discoveries have had such a large impact on and relevance to clinical medicine as the noninvasive measurement of the diastolic blood pressure. A number of gifted physiologists and clinicians were ineffectively in search of a noninvasive method to determine the diastolic pressure. Nonetheless, the quantification of the diastolic BP was not achieved by any of these clinical or physiologi...
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ژورنال
عنوان ژورنال: Circulation
سال: 2005
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.105.570069